Recombinant Human DDB1/CRBN Complex Protein

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Recombinant Human DDB1/CRBN Complex Protein

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Cat.No. : CRBN-001H
Product Overview : Recombinant Human DDB1/CRBN Complex Protein without tag was expressed in Spodoptera frugiperda, Sf 21 (baculovirus).
Description : This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : Insect cell
Species : Human
Bio-activity : Typical concentration to support in vitro applications will depend on experimental conditions.
Molecular Mass : 127 kDa (DDB1), 51 kDa (CRBN)
Purity : >95% by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
36 months from date of receipt, -70 centigrade as supplied.
6 months, -20 to -70 centigrade under sterile conditions after opening.
Storage Buffer : X mg/mL (X μM) in 50 mM HEPES pH 7.5, 200 mM NaCl, 10% (v/v), Glycerol, 1 mM DTT
Shipping : The product is shipped with dry ice or equivalent.
Gene Name : CRBN cereblon [ Homo sapiens (human) ]
Official Symbol : CRBN
Synonyms : CRBN; cereblon; MRT2; MRT2A; protein cereblon; protein x 0001
Gene ID : 51185
mRNA Refseq : NM_016302
Protein Refseq : NP_057386
MIM : 609262
UniProt ID : Q96SW2

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