Recombinant Human DDR2 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: DDR2-382H
• Product Overview: DDR2 MS Standard C13 and N15-labeled recombinant protein (NP_001014796) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in this gene are the cause of short limb-hand type spondylometaepiphyseal dysplasia. [provided by RefSeq, Aug 2017]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 96.7 kDa
• AA Sequence: MILIPRMLLVLFLLLPILSSAKAQV NPAICRYPLGMSGGQIPDEDITASS QWSESTAAKYGRLDSEEGDGAWCPE IPVEPDDLKEFLQIDLHTLHFITLV GTQGRHAGGHGIEFAPMYKINYSRD GTRWISWRNRHGKQVLDGNSNPYDI FLKDLEPPIVARFVRFIPVTDHSMN VCMRVELYGCVWLDGLVSYNAPAGQ QFVLPGGSIIYLNDSVYDGAVGYSM TEGLGQLTDGVSGLDDFTQTHEYHV WPGYDYVGWRNESATNGYIEIMFEF DRIRNFTTMKVHCNNMFAKGVKIFK EVQCYFRSEASEWEPNAISFPLVLD DVNPSARFVTVPLHHRMASAIKCQY HFADTWMMFSEITFQSDAAMYNNSE ALPTSPMAPTTYDPMLKVDDSNTRI LIGCLVAIIFILLAIIVIILWRQFW QKMLEKASRRMLDDEMTVSLSLPSD SSMFNNNRSSSPSEQGSNSTYDRIF PLRPDYQEPSRLIRKLPEFAPGEEE SGCSGVVKPVQPSGPEGVPHYAEAD IVNLQGVTGGNTYSVPAVTMDLLSG KDVAVEEFPRKLLTFKEKLGEGQFG EVHLCEVEGMEKFKDKDFALDVSAN QPVLVAVKMLRADANKNARNDFLKE IKIMSRLKDPNIIHLLAVCITDDPL CMITEYMENGDLNQFLSRHEPPNSS SSDVRTVSYTNLKFMATQIASGMKY LSSLNFVHRDLATRNCLVGKNYTIK IADFGMSRNLYSGDYYRIQGRAVLP IRWMSWESILLGKFTTASDVWAFGV TLWETFTFCQEQPYSQLSDEQVIEN TGEFFRDQGRQTYLPQPAICPDSVY KLMLSCWRRDTKNRPSFQEIHLLLL QQGDETRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DDR2 discoidin domain receptor tyrosine kinase 2 [ Homo sapiens (human) ]
• Official Symbol: DDR2
• Synonyms: DDR2; discoidin domain receptor tyrosine kinase 2; discoidin domain receptor family, member 2, NTRKR3, TYRO10; discoidin domain-containing receptor 2; TKT; tyrosylprotein kinase; hydroxyaryl-protein kinase; discoidin domain receptor 2; tyrosine-protein kinase TYRO10; CD167 antigen-like family member B; cell migration-inducing protein 20; migration-inducing gene 16 protein; receptor protein-tyrosine kinase TKT; discoidin domain receptor family, member 2; neurotrophic tyrosine kinase receptor related 3; neurotrophic tyrosine kinase, receptor-related 3; discoidin domain-containing receptor tyrosine kinase 2; MIG20a; NTRKR3; TYRO10
• Gene ID: 4921
• mRNA Refseq: NM_001014796
• Protein Refseq: NP_001014796
• MIM: 191311
• UniProt ID: Q16832