"DDX6" Related Products

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Recombinant Human DDX6 protein, MYC/DDK-tagged

Cat.No.: DDX6-45H
Product Overview: Recombinant Human DDX6 fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description: This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Source: HEK293
Species: Human
Tag : MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 54.2 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 [ Homo sapiens ]
Official Symbol: DDX6
Synonyms: DDX6; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp Glu Ala Asp) box polypeptide 6 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase, 54kD) , HLR2; probable ATP-dependent RNA helicase DDX6; RCK; DEAD box-6; oncogene RCK; DEAD box protein 6; ATP-dependent RNA helicase p54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD); P54; HLR2; FLJ36338;
Gene ID: 1656
mRNA Refseq: NM_004397
Protein Refseq: NP_004388
MIM: 600326
UniProt ID: P26196
Chromosome Location: 11q23.3
Pathway: Deadenylation-dependent mRNA decay, organism-specific biosystem; Decapping complex, organism-specific biosystem; Decapping complex, conserved biosystem; Gene Expression, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; mRNA Decay by 5 to 3 Exoribonuclease, organism-specific biosystem;
Function: ATP binding; ATP-dependent helicase activity; RNA binding; RNA helicase activity; helicase activity; hydrolase activity; nucleic acid binding; nucleotide binding; protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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