Recombinant Human DEF6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DEF6-4588H
• Product Overview: DEF6 MS Standard C13 and N15-labeled recombinant protein (NP_071330) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC and CDC42 that is highly expressed in B and T cells.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 73.7 kDa
• AA Sequence: MALRKELLKSIWYAFTALDVEKSGK VSKSQLKVLSHNLYTVLHIPHDPVA LEEHFRDDDDGPVSSQGYMPYLNKY ILDKVEEGAFVKEHFDELCWTLTAK KNYRADSNGNSMLSNQDAFRLWCLF NFLSEDKYPLIMVPDEVEYLLKKVL SSMSLEVSLGELEELLAQEAQVAQT TGGLSVWQFLELFNSGRCLRGVGRD TLSMAIHEVYQELIQDVLKQGYLWK RGHLRRNWAERWFQLQPSCLCYFGS EECKEKRGIIPLDAHCCVEVLPDRD GKRCMFCVKTATRTYEMSASDTRQR QEWTAAIQMAIRLQAEGKTSLHKDL KQKRREQREQRERRRAAKEEELLRL QQLQEEKERKLQELELLQEAQRQAE RLLQEEEERRRSQHRELQQALEGQL REAEQARASMQAEMELKEEEAARQR QRIKELEEMQQRLQEALQLEVKARR DEESVRIAQTRLLEEEEEKLKQLMQ LKEEQERYIERAQQEKEELQQEMAQ QSRSLQQAQQQLEEVRQNRQRADED VEAAQRKLRQASTNVKHWNVQMNRL MHPIEPGDKRPVTSSSFSGFQPPLL AHRDSSLKRLTRWGSQGNRTPSPNS NEQQKSLNGGDEAPAPASTPQEDKL DPAPENTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DEF6 DEF6 guanine nucleotide exchange factor [ Homo sapiens (human) ]
• Official Symbol: DEF6
• Synonyms: DEF6; differentially expressed in FDCP 6 homolog (mouse); differentially expressed in FDCP (mouse homolog) 6; differentially expressed in FDCP 6 homolog; IBP; SLAT; SWAP 70 like adaptor protein of T cells; SWAP70L; DEF-6; IRF4-binding protein; SWAP-70-like adaptor protein of T cells
• Gene ID: 50619
• mRNA Refseq: NM_022047
• Protein Refseq: NP_071330
• MIM: 610094
• UniProt ID: Q9H4E7