Recombinant Human Dehydrogenase/Reductase (SDR Family) Member 9, His-tagged

• Cat.No.: DHRS9-1561H
• Product Overview: Recombinant human DHRS9 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Cat. No.: DHRS9-1561H
• Description: DHRS9, also known as dehydrogenase/reductase SDR family member 9, functions as a homotetramer that converts both 3-alpha-tetrahydroprogesterone (allopregnanolone) and 3-alpha-androstanediol to dihydroxyprogesterone and is thought to play a role in retinoic acid biosynthesis.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 2mM DTT, 0.1mM PMSF.
• Molecular Weight: 35.9 kDa (327aa), confirmed by MALDI-TOF.
• Purity: >90% by SDS-PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMRKGKL KIEDITDKYI FITGCDSGFG NLAARTFDKK GFHVIAACLT ESGSTALKAE TSERLRTVLLDVTDPENVKR TAQWVKNQVG EKGLWGLINN AGVPGVLAPT DWLTLEDYRE PIEVNLFGLI SVTLNMLPLV KKAQGRVINV SSVGGRLAIVGGGYTPSKYA VEGFNDSLRR DMKAFGVHVS CIEPGLFKTN LADPVKVIEK KLAIWEQLSP DIKQQYGEGY IEKSLDKLKG NKSYVNMDLSPVVECMDHAL TSLFPKTHYA AGKDAKIFWI PLSHMPAALQ DFLLLKQKAE LANPKAV
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Metabolic pathways; Retinol metabolism

Gene Information

• Gene Name: DHRS9 dehydrogenase/reductase (SDR family) member 9 [ Homo sapiens ]
• Official Symbol: DHRS9
• Synonyms: DHRS9; dehydrogenase/reductase (SDR family) member 9; RDHL; RDH15; RDHTBE; SDR9C4; RETSDR8; 3ALPHA-HSD; 3-alpha-HSD; OTTHUMP00000163043; OTTHUMP00000204923; OTTHUMP00000204925; OTTHUMP00000204926; OTTHUMP00000205057; retinol dehydrogenase homolog; 3-alpha hydroxysteroid dehydrogenase; short-chain dehydrogenase/reductase retSDR8; NADP-dependent retinol dehydrogenase/reductase; short chain dehydrogenase/reductase family 9C, member 4; 3alpha-HSD; dehydrogenase/reductase SDR family member 9; EC 1.1; RDH-E2; EC 1.1.1; EC 1.1.1.105
• Gene ID: 10170
• mRNA Refseq: NM_001142270
• Protein Refseq: NP_001135742
• MIM: 612131
• UniProt ID: Q9BPW9
• Chromosome Location: 2q31.1
• Function: alcohol dehydrogenase (NAD) activity; binding NAS PubMed; retinol dehydrogenase activity; testosterone dehydrogenase (NAD+) activity