Recombinant Human DEK Protein, GST-tagged

• Cat.No.: DEK-2529H
• Product Overview: Human DEK full-length ORF (BAG35503.1, 1 a.a. - 375 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 67.65 kDa
• AA Sequence: MSASAPAAEGEGTPTQPASEKEPEM PGPREESEEEEDEDDEEEEEEEKEK SLIVEGKREKKKVERLTMQVSSLQR EPFTIAQGKGQKLCEIERIHFFLSK KKTDELRNLHKLLYNRPGTVSSLKK NVGQFSGFPFEKGSVQYKKKEEMLK KFRNAMLKSICEVLDLERSGVNSEL VKRILNFLMHPKPSGKPLPKSKKTC SKGSKKERNSSGMARKAKRTKCPEI LSDESSSDEDEKKNKEESSDDEDKE SEEEPPKKTAKREKPKQKATSKSKK SVKSANVKKADSSTTKKNQNSSKKE SESEDSSDDEPLIKKLKKPPTDEEL KETIKKLLASANLEEVTMKQICKKV YENYPTYDLTERKDFIKTTVKELIS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DEK DEK oncogene [ Homo sapiens ]
• Official Symbol: DEK
• Synonyms: DEK; DEK oncogene; DEK oncogene (DNA binding); protein DEK; D6S231E
• Gene ID: 7913
• mRNA Refseq: NM_001134709
• Protein Refseq: NP_001128181
• MIM: 125264
• UniProt ID: P35659