Human DEK Knockdown Cell Lysate

• Cat.No.: DEK-336HKCL
• Product Overview: WB-validated DEK Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 43 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg DEK KD HeLa cell lysate
• Protein Families: Druggable Genome, Transcription Factors
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: DEK DEK oncogene [ Homo sapiens (human) ]
• Official Symbol: DEK
• Synonyms: DEK; DEK oncogene; DEK oncogene (DNA binding); protein DEK; D6S231E
• Gene ID: 7913
• mRNA Refseq: NM_001134709
• Protein Refseq: NP_001128181
• MIM: 125264
• UniProt ID: P35659