Recombinant Human DENND4B Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DENND4B-784H
• Product Overview: DENND4B MS Standard C13 and N15-labeled recombinant protein (NP_055671) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 163.7 kDa
• AA Sequence: MAEERPPRLVDYFVVAGLAGNGAPI PEETWVPEPSGPLRPPRPAEPITDV AVIARALGEEVPQGYTCIQASAGGH PLELSAGLLGGTQPVICYRRGRDKP PLVELGVLYEGKERPKPGFQVLDTT PYSHSANLAPPGPGHPRTYLTYRRA AEGAGLHALGITDLCLVLPSKGEGT PHTYCRLPRNLNPGMWGPAVYLCYK VGLAKANTLVYEAELLGRYPEEDNE AFPLPESVPVFCLPMGATIECWPAQ TKYPVPVFSTFVLTGAAGDKVYGAA LQFYEAFPRARLSERQARALGLLSA VERGRALGGRAVRSRRAIAVLSRWP AFPAFRAFLTFLYRYSVSGPHRLPL EAHISHFIHNVPFPSPQRPRILVQM SPYDNLLLCQPVSSPLPLSGASFLQ LLQSLGPELAITLLLAVLTEHKLLV HSLRPDLLTSVCEALVSMIFPLHWQ CPYIPLCPLVLADVLSAPVPFIVGI HSSYFDLHDPPADVICVDLDTNTLF QTEEKKLLSPRTLPRRPYKVLLATL TNLYQQLDQTYTGPEEEASLEFLLT DYEAVCGRRARLEREVQGAFLRFMA CLLKGYRVFLRPLTQAPSEGARDVD NLFFLQGFLKSRERSSHKLYSQLLH TQMFSQFIEECSFGSARHAALEFFD SCVEKVHPEQEKPEPTPLVELEELS GSELTVFITPPEEPALPEGSESTPQ YCYDGFPELRAELFESLQEQPGALP VPGPSRSAPSSPAPRRTKQEMKVAQ RMAQKSAAVPELWARCLLGHCYGLW FLCLPAYVRSAPSRVQALHTAYHVL RQMESGKVVLPDEVCYRVLMQLCSH YGQPVLSVRVMLEMRQAGIVPNTIT YGYYNKAVLESKWPSGTPGGRLRWA KLRNVVLGAAQFRQPLRERQQQQQQ QQQQQQQQQQEQVSAHQEAGSSQAE PYLERPSPTRPLQRQTTWAGRSLRD PASPPGRLVKSGSLGSARGAQPTVE AGVAHMIEALGVLEPRGSPVPWHDG SLSDLSLTGEEPLPGGSPGGSGSAL SAQSTEALEGLSGRGPKAGGRQDEA GTPRRGLGARLQQLLTPSRHSPASR IPPPELPPDLPPPARRSPMDSLLHP RERPGSTASESSASLGSEWDLSESS LSNLSLRRSSERLSDTPGSFQSPSL EILLSSCSLCRACDSLVYDEEIMAG WAPDDSNLNTTCPFCACPFVPLLSV QTLDSRPSVPSPKSAGASGSKDAPV PGGPGPVLSDRRLCLALDEPQLCNG HMGGASRRVESGAWAYLSPLVLRKE LESLVENEGSEVLALPELPSAHPII FWNLLWYFQRLRLPSILPGLVLASC DGPSHSQAPSPWLTPDPASVQVRLL WDVLTPDPNSCPPLYVLWRVHSQIP QRVVWPGPVPASLSLALLESVLRHV GLNEVHKAVGLLLETLGPPPTGLHL QRGIYREILFLTMAALGKDHVDIVA FDKKYKSAFNKLASSMGKEELRHRR AQMPTPKAIDCRKCFGAPPECTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DENND4B DENN/MADD domain containing 4B [ Homo sapiens (human) ]
• Official Symbol: DENND4B
• Synonyms: DENND4B; DENN domain containing 4B; KIAA0476; DENN domain-containing protein 4B; DENN/MADD domain containing 4B
• Gene ID: 9909
• mRNA Refseq: NM_014856
• Protein Refseq: NP_055671
• UniProt ID: O75064