| Description : |
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
90.4 kDa |
| AA Sequence : |
MTNQEKWAHLSPSEFSQLQKYAEYS TKKLKDVLEEFHGNGVLAKYNPEGK QDILNQTIDFEGFKLFMKTFLEAEL PDDFTAHLFMSFSNKFPHSSPMVKS KPALLSGGLRMNKGAITPPRTTSPA NTCSPEVIHLKDIVCYLSLLERGRP EDKLEFMFRLYDTDGNGFLDSSELE NIISQMMHVAEYLEWDVTELNPILH EMMEEIDYDHDGTVSLEEWIQGGMT TIPLLVLLGLENNVKDDGQHVWRLK HFNKPAYCNLCLNMLIGVGKQGLCC SFCKYTVHERCVARAPPSCIKTYVK SKRNTDVMHHYWVEGNCPTKCDKCH KTVKCYQGLTGLHCVWCQITLHNKC ASHLKPECDCGPLKDHILPPTTICP VVLQTLPTSGVSVPEERQSTVKKEK SGSQQPNKVIDKNKMQRANSVTVDG QGLQVTPVPGTHPLLVFVNPKSGGK QGERIYRKFQYLLNPRQVYSLSGNG PMPGLNFFRDVPDFRVLACGGDGTV GWVLDCIEKANVGKHPPVAILPLGT GNDLARCLRWGGGYEGENLMKILKD IENSTEIMLDRWKFEVIPNDKDEKG DPVPYSIINNYFSIGVDASIAHRFH IMREKHPEKFNSRMKNKFWYFEFGT SETFSATCKKLHESVEIECDGVQID LINISLEGIAILNIPSMHGGSNLWG ESKKRRSHRRIEKKGSDKRTTVTDA KELKFASQDLSDQLLEVVGLEGAME MGQIYTGLKSAGRRLAQCSCVVIRT SKSLPMQIDGEPWMQTPCTIKITHK NQAPMLMGPPPKTGLFCSLVKRTRN RSKETRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
