| Description : |
This gene encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in signaling cascades. Their cellular concentrations are regulated by the encoded protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
134.3 kDa |
| AA Sequence : |
MAAAAGAPPPGPPQPPPPPPPEESS DSEPEAEPGSPQKLIRKVSTSGQIR QKTIIKEGMLTKQNNSFQRSKRRYF KLRGRTLYYAKTAKSIIFDEVDLTD ASVAESSTKNVNNSFTVITPCRKLI LCADNRKEMEDWIAALKTVQNREHF EPTQYSMDHFSGMHNWYACSHARPT YCNVCREALSGVTSHGLSCEVCKFK AHKRCAVRATNNCKWTTLASIGKDI IEDADGIAMPHQWLEGNLPVSAKCT VCDKTCGSVLRLQDWRCLWCKAMVH TSCKESLLTKCPLGLCKVSVIPPTA LNSIDSDGFWKASCPPSCTSPLLVF VNSKSGDNQGVKFLRRFKQLLNPAQ VFDLMNGGPHLGLRLFQKFDTFRIL VCGGDGSVGWVLSEIDSLNLHKQCQ LGVLPLGTGNDLARVLGWGSACDDD TQLPQILEKLERASTKMLDRWSVMA YEAKLPRQASSSTVTEDFSEDSEVQ QILFYEDSVAAHLSKILTSDQHSVV ISSAKVLCETVKDFVARVGKAYEKT TESSEESEVMAKKCSVLKEKLDSLL KTLDDESQASSSLPNPPPTIAEEAE DGDGSGSICGSTGDRLVASACPARP QIFRPREQLMLRANSLKKAIRQIIE HTEKAVDEQNAQTQEQEGFVLGLSE SEEKMDHRVCPPLSHSESFGVPKGR SQRKVSKSPCEKLISKGSLSLGSSA SLPPQPGSRDGLPALNTKILYPNVR AGMSGSLPGGSVISRLLINADPFNS EPETLEYYTEKCVMNNYFGIGLDAK ISLDFNNKRDEHPEKCRSRTKNMMW YGVLGTKELLHRTYKNLEQKVLLEC DGRPIPLPSLQGIAVLNIPSYAGGT NFWGGTKEDDTFAAPSFDDKILEVV AVFGSMQMAVSRVIRLQHHRIAQCR TVKISILGDEGVPVQVDGEAWVQPP GYIRIVHKNRAQTLTRDRAFESTLK SWEDKQKCELPRPPSCSLHPEMLSE EEATQMDQFGQAAGVLIHSIREIAQ SHRDMEQELAHAVNASSKSMDRVYG KPRTTEGLNCSFVLEMVNNFRALRS ETELLLSGKMALQLDPPQKEQLGSA LAEMDRQLRRLADTPWLCQSAEPGD EESVMLDLAKRSRSGKFRLVTKFKK EKNNKNKEAHSSLGAPVHLWGTEEV AAWLEHLSLCEYKDIFTRHDIRGSE LLHLERRDLKDLGVTKVGHMKRILC GIKELSRSAPAVEATRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
