Recombinant Human DHDH Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DHDH-6662H
• Product Overview: DHDH MS Standard C13 and N15-labeled recombinant protein (NP_055290) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 36.4 kDa
• AA Sequence: MALRWGIVSVGLISSDFTAVLQTLP RSEHQVVAVAARDLSRAKEFAQKHD IPKAYGSYEELAKDPSVEVAYIGTQ HPQHKAAVMLCLAAGKAVLCEKPTG VNAAEVREMVAEARSRALFLMEAIW TRFFPASEALRSVLAQGTLGDLRVA RAEFGKNLIHVPRAVDRAQAGGALL DIGIYCVQFTSMVFGGQKPEKISVV GRRHETGVDDTVTVLLQYPGEVHGS FTCSITVQLSNTASVSGTKGMVQLL NPCWCPTELVVKGEHKEFPLPPVPK DCNFDNGAGMSYEAKHVWECLRKGM KESPVIPLSESELLADILEEVRKAI GVTFPQDKRSGPTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DHDH dihydrodiol dehydrogenase [ Homo sapiens (human) ]
• Official Symbol: DHDH
• Synonyms: DHDH; dihydrodiol dehydrogenase (dimeric); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; HUM2DD; D-xylose 1-dehydrogenase; 3-deoxyglucosone reductase; D-xylose-NADP dehydrogenase; 2DD
• Gene ID: 27294
• mRNA Refseq: NM_014475
• Protein Refseq: NP_055290
• MIM: 606377
• UniProt ID: Q9UQ10