Recombinant Human Di-Ubiquitin Protein (K48-Linked), Biotinylated
Cat.No. : | Di-Ubiquitin-37H |
Product Overview : | Recombinant Human Di-Ubiquitin Protein (K48-Linked), Biotinylated without tag was expressed in E. coli |
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Description : | Poly-ubiquitylation of target proteins through linkage at K48, is now the most thoroughly studied of the various chain linkages, and we once considered the hallmark of this post-translational modification. It is now clear that many, if not all, poly-Ub chain topologies likely play distinct and important roles in regulating cellular processes. Nevertheless, the K48 linkage remains a critical pathway for cells to maintain homeostasis through proteolytic degradation, and as such remains very intriguing for the study of DUBs that play a role in the degradation, as well as the proteasome itself. These diubiquitin chains generated from the enzymatic linkage of wild-type ubiquitin through lysine 48. The most distal ubiquitin contains an arginine substitution for the lysine at position 48, limiting chain length. |
Source : | E. coli |
Species : | Human |
Tag : | Tag Free |
Form : | Liquid |
Molecular Mass : | 17,139.7 Da |
Applications : | Optimization of pull-down conditions for anti-K48 TUBE and anti K63-TUBE reagents |
Storage : | At -80 centigrade, avoid freeze/thaw cycles |
Storage Buffer : | Phosphate Buffered Saline pH 7.4 |
Official Symbol : | Di-Ubiquitin |
Synonyms : | Di-Ubiquitin; Ub2 |
Official Symbol : | Di-Ubiquitin |
Synonyms : | Di-Ubiquitin; Ub2 |
Products Types
◆ Recombinant Protein | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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