Recombinant Human DIS3L Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human DIS3L Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : DIS3L-5927H
Product Overview : DIS3L MS Standard C13 and N15-labeled recombinant protein (NP_588616) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The cytoplasmic RNA exosome complex degrades unstable mRNAs and is involved in the regular turnover of other mRNAs. The protein encoded by this gene contains 3'-5' exoribonuclease activity and is a catalytic component of this complex.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 111.1 kDa
AA Sequence : MQTACQAVQH QRGRRQYNKL RNLLKDARHD CILFANEFQQ CCYLPRERGE SMEKWQTRSI YNAAVWYYHH CQDRMPIVMV TEDEEAIQQY GSETEGVFVI TFKNYLDNFW PDLKAAHELC DSILQSRRER ENESQESHGK EYPEHLPLEV LEAGIKSGRY IQGILNVNKH RAQIEAFVRL QGASSKDSDL VSDILIHGMK ARNRSIHGDV VVVELLPKNE WKGRTVALCE NDCDDKASGE SPSEPMPTGR VVGILQKNWR DYVVTFPSKE EVQSQGKNAQ KILVTPWDYR IPKIRISTQQ AETLQDFRVV VRIDSWESTS VYPNGHFVRV LGRIGDLEGE IATILVENSI SVIPFSEAQM CEMPVNTPES PWKVSPEEEQ KRKDLRKSHL VFSIDPKGCE DVDDTLSVRT LNNGNLELGV HIADVTHFVA PNSYIDIEAR TRATTYYLAD RRYDMLPSVL SADLCSLLGG VDRYAVSIMW ELDKASYEIK KVWYGRTIIR SAYKLFYEAA QELLDGNLSV VDDIPEFKDL DEKSRQAKLE ELVWAIGKLT DIARHVRAKR DGCGALELEG VEVCVQLDDK KNIHDLIPKQ PLEVHETVAE CMILANHWVA KKIWESFPHQ ALLRQHPPPH QEFFSELREC AKAKGFFIDT RSNKTLADSL DNANDPHDPI VNRLLRSMAT QAMSNALYFS TGSCAEEEFH HYGLALDKYT HFTSPIRRYS DIVVHRLLMA AISKDKKMEI KGNLFSNKDL EELCRHINNR NQAAQHSQKQ STELFQCMYF KDKDPATEER CISDGVIYSI RTNGVLLFIP RFGIKGAAYL KNKDGLVISC GPDSCSEWKP GSLQRFQNKI TSTTTDGESV TFHLFDHVTV RISIQASRCH SDTIRLEIIS NKPYKIPNTE LIHQSSPLLK SELVKEVTKS VEEAQLAQEV KVNIIQEEYQ EYRQTKGRSL YTLLEEIRDL ALLDVSNNYG ITRTRPLEQK LISEEDLAAN DILDYKDDDD KV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : DIS3L DIS3 like exosome 3'-5' exoribonuclease [ Homo sapiens (human) ]
Official Symbol : DIS3L
Synonyms : DIS3L; DIS3 mitotic control homolog (S. cerevisiae)-like; DIS3-like exonuclease 1; FLJ38088; KIAA1955; MGC4562; DIS3L1;
Gene ID : 115752
mRNA Refseq : NM_133375
Protein Refseq : NP_588616
MIM : 614183
UniProt ID : Q8TF46

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