Recombinant Human DLG4 protein, MYC/DDK-tagged DLG4-152H

Recombinant Human DLG4 protein, MYC/DDK-tagged


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Recombinant Human DLG4 protein, MYC/DDK-tagged

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Cat.No. : DLG4-152H
Product Overview : Recombinant Human DLG4, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description : This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 85.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : DLG4 discs, large homolog 4 (Drosophila) [ Homo sapiens ]
Official Symbol : DLG4
Synonyms : DLG4; discs, large homolog 4 (Drosophila); disks large homolog 4; PSD 95; PSD95; SAP 90; SAP90; discs large homolog 4; Tax interaction protein 15; synapse-associated protein 90; postsynaptic density protein 95; post-synaptic density protein 95; SAP-90; FLJ97752; FLJ98574;
Gene ID : 1742
mRNA Refseq : NM_001365
Protein Refseq : NP_001356
MIM : 602887
UniProt ID : P78352
Chromosome Location : 17p13.1
Pathway : Activation of Ca-permeable Kainate Receptor, organism-specific biosystem; Activation of Kainate Receptors upon glutamate binding, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Axon guidance, organism-specific biosystem; CREB phosphorylation through the activation of CaMKII, organism-specific biosystem; CREB phosphorylation through the activation of Ras, organism-specific biosystem; Cocaine addiction, organism-specific biosystem;
Function : protein C-terminus binding; protein binding; scaffold protein binding;

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