Recombinant Human DLK1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human DLK1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : DLK1-3124H
Product Overview : DLK1 MS Standard C13 and N15-labeled recombinant protein (NP_003827) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 41.2 kDa
AA Sequence : MTATEALLRV LLLLLAFGHS TYGAECFPAC NPQNGFCEDD NVCRCQPGWQ GPLCDQCVTS PGCLHGLCGE PGQCICTDGW DGELCDRDVR ACSSAPCANN GTCVSLDDGL YECSCAPGYS GKDCQKKDGP CVINGSPCQH GGTCVDDEGR ASHASCLCPP GFSGNFCEIV ANSCTPNPCE NDGVCTDIGG DFRCRCPAGF IDKTCSRPVT NCASSPCQNG GTCLQHTQVS YECLCKPEFT GLTCVKKRAL SPQQVTRLPN GYGLAYRLTP GVHELPVQQP EHRILKVSMK ELNKKTPLLT EGQAICFTIL GVLTSLVVLG TVGIVFLNKC ETWVSNLRYN HMLRKKKNLL LQYNSGEDLA VNIIFPEKID MTTFSKEAGD EEITRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : DLK1 delta like non-canonical Notch ligand 1 [ Homo sapiens (human) ]
Official Symbol : DLK1
Synonyms : DLK1; delta-like 1 homolog (Drosophila); delta like homolog (Drosophila); protein delta homolog 1; Delta1; FA1; pG2; Pref 1; ZOG; DLK-1; secredeltin; fetal antigen 1; preadipocyte factor 1; DLK; PREF1; Pref-1;
Gene ID : 8788
mRNA Refseq : NM_003836
Protein Refseq : NP_003827
MIM : 176290
UniProt ID : P80370

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