Recombinant Human DMD protein, MYC/DDK-tagged

• Cat.No.: DMD-12H
• Product Overview: Recombinant Human DMD, transcript variant Dp140b, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 143 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DMD dystrophin [ Homo sapiens ]
• Official Symbol: DMD
• Synonyms: DMD; dystrophin; dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272; BMD; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; muscular dystrophy; Duchenne and Becker types; CMD3B
• Gene ID: 1756
• mRNA Refseq: NM_004021
• Protein Refseq: NP_004012
• MIM: 300377
• UniProt ID: P11532
• Chromosome Location: Xp21.2
• Pathway: Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; Hypertrophic cardiomyopathy (HCM), conserved biosystem; Muscle contraction, organism-specific biosystem
• Function: PDZ domain binding; actin binding; actin binding; beta-dystroglycan binding; dystroglycan binding; integrin binding; metal ion binding; nitric-oxide synthase binding; protein binding; structural constituent of cytoskeleton; structural constituent of muscle; structural constituent of muscle; zinc ion binding