Recombinant Human DNA-damage-inducible Transcript 3
Cat.No. : | DDIT3-130H |
Product Overview : | Recombinant Human DNA-damage-inducible transcript 3 protein expressed inE.coliencodes full length amino acids and has a molecular mass of 52 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | DDIT3-130H |
Description : | GADD 153 has been described as a growth arrest and DNA damage-inducible gene that encodes a C/EBP-related nuclear protein. GADD153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and merabolic perturbations. GADD153 functions to block cells in G1 to S phase in cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD153 dimers away from "classical" C/EBP binding sites, recognizing instead unique "nonclassical" sites. |
Source : | E.coli. |
Formulation : | Recombinant Human GADD153 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol. |
Application : | •ELISA •Inhibition Assays •Western Blotting. |
Characterization : | On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 52 kDa. |
Storage & Stability : | Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months. |
Publication : |
Is there a common upstream link for autophagic and apoptotic cell death in human high-grade gliomas? (2011)
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Gene Name : | DDIT3 DNA-damage-inducible transcript 3 [ Homo sapiens ] |
Synonyms : | DDIT3; DNA-damage-inducible transcript 3; CHOP; CEBPZ; CHOP10; GADD153; MGC4154; C/EBP zeta; DDIT-3; Growth arrest and DNA-damage-inducible protein GADD153; C/EBP-homologous protein; C/EBP homologous protein; CCAAT/enhancer-binding protein homologous protein; growth arrest- and DNA damage-inducible |
Gene ID : | 1649 |
mRNA Refseq : | NM_004083 |
Protein Refseq : | NP_004074 |
MIM : | 126337 |
UniProt ID : | P35638 |
Chromosome Location : | 12q13.1-q13.2 |
Pathway : | MAPK signaling pathway; Diabetes pathways |
Function : | protein dimerization activity; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity |
Products Types
◆ Recombinant Protein | ||
DDIT3-1031R | Recombinant Rhesus Macaque DDIT3 Protein, His (Fc)-Avi-tagged | +Inquiry |
DDIT3-217H | Recombinant Human DDIT3 Protein, GST/His-tagged | +Inquiry |
DDIT3-2255M | Recombinant Mouse DDIT3 Protein, His (Fc)-Avi-tagged | +Inquiry |
DDIT3-2442H | Recombinant Human DDIT3 Protein, GST-tagged | +Inquiry |
DDIT3-1361H | Recombinant Human DNA-damage-inducible Transcript 3, GST-tagged | +Inquiry |
◆ Lysates | ||
DDIT3-7027HCL | Recombinant Human DDIT3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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