Recombinant Human DNAAF3 Protein, GST-tagged

• Cat.No.: DNAAF3-2721H
• Product Overview: Human DNAAF3 full-length ORF ( AAH16843.1, 1 a.a. - 541 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is required for the assembly of axonemal inner and outer dynein arms and plays a role in assembling dynein complexes for transport into cilia. Defects in this gene are a cause of primary ciliary dyskinesia type 2 (CILD2). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 85.8 kDa
• AA Sequence: MTTPAGSGSGFGSVSWWGLSPALDL QAESPPVDPDSQADTVHSNPELDVL LLGSVDGRHLLRTLSRAKFWPRRRF NFFVLENNLEAVARHMLIFSLALEE PEKMGLQERSETFLEVWGNALLRPP VAAFVRAQADLLAHLVPEPDRLEEQ LPWLSLRALKFRERDALEAVFRFWA GGEKGPQAFPMSRLWDSRLRHYLGS RYDARRGVSDWDLRMKLHDRGAQVI HPQEFRRWRDTGVAFELRDSSAYHV PNRTLASGRLLSYRGERVAARGYWG DIATGPFVAFGIEADDESLLRTSNG QPVKTAGEITQHNVTELLRDVAAWG RARATGGDLEEQQHAEGSPEPGTPA APTPESFTVHFLPLNSAQTLHHKSC YNGRFQLLYVACGMVHLLIPELGAC VAPGGNLIVELARYLVDVRQEQLQG FNTRVRELAQAAGFAPQTGARPSET FARFCKSQESALGNTVPAVEPGTPP LDILAQPLEASNPALEGLTQPLQGG TPHCEPCQLPSESPGSLSEVLAQPQ GALAPPNCESDSKTGV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DNAAF3 dynein axonemal assembly factor 3 [ Homo sapiens (human) ]
• Official Symbol: DNAAF3
• Synonyms: DNAAF3; dynein axonemal assembly factor 3; Dynein Axonemal Assembly Factor 3; C19orf51; Chromosome 19 Open Reading Frame 51; Dynein, Axonemal, Assembly Factor 3; Dynein (Axonemal) Assembly Factor 3; Dynein Assembly Factor 3, Axonemal; Ciliary Dyskinesia, Primary 2; UPF0470 Protein C19orf51; CILD2; DAB1; PF22; PCD; dynein assembly factor 3, axonemal; UPF0470 protein C19orf51
• Gene ID: 352909
• mRNA Refseq: NM_001256714
• Protein Refseq: NP_001243643
• MIM: 614566
• UniProt ID: Q8N9W5