Recombinant Human DNAJB11, His-tagged

• Cat.No.: DNAJB11-28367TH
• Product Overview: Recombinant fragment, corresponding to amino acids 44-358 of Human DNAJB11 with an N terminal His tag. Predicted mwt: 37 kDa

Specification

• Description: DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Widely expressed.
• Form: Lyophilised:Reconstitute with 107 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: AYRKLALQLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKR KQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGTP RQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVAR QAPGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNV KLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPG DLRFRIKVVKHPIFERRGDDLYTNVTISLVESLVGFEMDI THLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIK GSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYN GLQGY
• Sequence Similarities: Contains 1 J domain.

Gene Information

• Gene Name: DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 [ Homo sapiens ]
• Official Symbol: DNAJB11
• Synonyms: DNAJB11; DnaJ (Hsp40) homolog, subfamily B, member 11; dnaJ homolog subfamily B member 11; EDJ; ERdj3; HEDJ
• Gene ID: 51726
• mRNA Refseq: NM_016306
• Protein Refseq: NP_057390
• MIM: 611341
• Uniprot ID: Q9UBS4
• Chromosome Location: 3q27
• Pathway: Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem; Unfolded Protein Response, organism-specific biosystem
• Function: heat shock protein binding; unfolded protein binding