Recombinant Human DNAJB4 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human DNAJB4 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : DNAJB4-2926H
Product Overview : DNAJB4 MS Standard C13 and N15-labeled recombinant protein (NP_008965) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 37.8 kDa
AA Sequence : MGKDYYCILG IEKGASDEDI KKAYRKQALK FHPDKNKSPQ AEEKFKEVAE AYEVLSDPKK REIYDQFGEE GLKGGAGGTD GQGGTFRYTF HGDPHATFAA FFGGSNPFEI FFGRRMGGGR DSEEMEIDGD PFSAFGFSMN GYPRDRNSVG PSRLKQDPPV IHELRVSLEE IYSGCTKRMK ISRKRLNADG RSYRSEDKIL TIEIKKGWKE GTKITFPREG DETPNSIPAD IVFIIKDKDH PKFKRDGSNI IYTAKISLRE ALCGCSINVP TLDGRNIPMS VNDIVKPGMR RRIIGYGLPF PKNPDQRGDL LIEFEVSFPD TISSSSKEVL RKHLPASTRT RPLEQKLISE EDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 [ Homo sapiens (human) ]
Official Symbol : DNAJB4
Synonyms : DNAJB4; DnaJ (Hsp40) homolog, subfamily B, member 4; dnaJ homolog subfamily B member 4; HLJ1; HSP40 homolog; heat shock protein 40 homolog; human liver DnaJ-like protein; DnaJ-like heat shock protein 40; heat shock 40 kDa protein 1 homolog; DjB4; DNAJW;
Gene ID : 11080
mRNA Refseq : NM_007034
Protein Refseq : NP_008965
MIM : 611327
UniProt ID : Q9UDY4

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