Recombinant Human DNASE1L3 Protein, Full Length, N-GST and C-His tagged

• Cat.No.: DNASE1L3-13HFL
• Product Overview: Purified recombinant protein of Human deoxyribonuclease I-like 3 (DNASE1L3), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli.

Specification

• Description: This gene encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: E. coli
• Species: Human
• Tag: N-GST, C-His
• Protein length: Full Length
• Molecular Mass: 35.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: > 0.05 μg/μL as determined by microplate BCA method
• Storage Buffer: 50 mM Tris-HCl, pH 8.0, 8 M urea

Gene Information

• Gene Name: DNASE1L3 deoxyribonuclease I-like 3 [ Homo sapiens (human) ]
• Official Symbol: DNASE1L3
• Synonyms: DNASE1L3; deoxyribonuclease I-like 3; deoxyribonuclease gamma; DNAS1L3; DNase gamma; LSD; LS-DNase; DNase I-like 3; Liver and spleen DNase; DNase I homolog protein 2; DNase I homolog protein DHP2; deoxyribonuclease I-like III; DHP2; SLEB16
• Gene ID: 1776
• mRNA Refseq: NM_001256560
• Protein Refseq: NP_001243489
• MIM: 602244
• UniProt ID: Q13609