Recombinant Human DNM1L Protein, Myc/DDK-tagged

• Cat.No.: DNM1L-8494H
• Product Overview: Recombinant protein of human dynamin 1-like (DNM1L), transcript variant 2 with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Description: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 79.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: DNM1L dynamin 1 like [ Homo sapiens (human) ]
• Official Symbol: DNM1L
• Synonyms: DNM1L; dynamin 1 like; DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV; dynamin-1-like protein; Dnm1p/Vps1p-like protein; dynamin family member proline-rich carboxyl-terminal domain less; dynamin-like protein 4; dynamin-like protein IV; dynamin-related protein 1; EC 3.6.5.5
• Gene ID: 10059
• mRNA Refseq: NM_012063
• Protein Refseq: NP_036193
• MIM: 603850
• UniProt ID: O00429