Recombinant Human DOC2B, GST-tagged

• Cat.No.: DOC2B-12115H
• Product Overview: Recombinant Human DOC2B protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 36-126a.a.
• Description: There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DOC2B double C2-like domains, beta [ Homo sapiens ]
• Official Symbol: DOC2B
• Synonyms: DOC2B; double C2-like domains, beta; DOC2BL, double C2 like domains, beta like; double C2-like domain-containing protein beta; doc2-beta; DOC2BL
• Gene ID: 8447
• mRNA Refseq: NM_003585
• Protein Refseq: NP_003576
• MIM: 604568
• UniProt ID: Q14184
• Chromosome Location: 17p13.3
• Function: calcium-dependent phospholipid binding; syntaxin binding; transporter activity