Recombinant Human DOCK2 Protein, GST-tagged

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Recombinant Human DOCK2 Protein, GST-tagged

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Cat.No. : DOCK2-2805H
Product Overview : Human DOCK2 full-length ORF ( AAH16996, 1 a.a. - 336 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 62.7 kDa
AA Sequence : MCVCAEDGKT LPVAVPIEDM QRIHLRFMFR HRSSLESKDK GEKNFAMSYV KLMKEDGTTL HDGFHDLVVL KGDSKKMEDA SAYLTLPSYR HHVENKGATL SRSSSSVGGL SVSSRDVFSI STLVCSTKLT QNVGLLGLLK WRMKPQLEES MRRLFESINN LMKSQYKTTI LLQVAALKYI PSVLHDVEMV FDAKLLSQLL YEFYTCIPPV KLQKQKVQSM NEIVQSNLFK KQECRDILLP VITKELKELL EQKDDMQHQV LERKYCVELL NSILEVLSYQ DAAFTYHHIQ EIMVQLLRTV NRTVITMGRD HILIGACCNC GFPSSTPHSL IQWLWG
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : DOCK2 dedicator of cytokinesis 2 [ Homo sapiens ]
Official Symbol : DOCK2
Synonyms : DOCK2; dedicator of cytokinesis 2; dedicator of cyto kinesis 2; dedicator of cytokinesis protein 2; KIAA0209; dedicator of cyto-kinesis 2; FLJ46592;
Gene ID : 1794
mRNA Refseq : NM_004946
Protein Refseq : NP_004937
MIM : 603122
UniProt ID : Q92608

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