Recombinant Human DOCK5 Protein, His-tagged

• Cat.No.: DOCK5-1367H
• Product Overview: Recombinant Human DOCK5 Protein (Ala1749-Gln1870) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family act as guanine nucleotide exchange factors for small Rho family G proteins. The protein encoded by this gene is thought to associate with adaptors CRK and CRKL, and function in regulation of intestinal epithelial cell spreading and migration on collagen IV. Similar proteins in mouse and zebrafish also function in myoblast fusion.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 16.6 kDa
  Accurate Molecular Mass: 17 kDa
• Protein length: Ala1749-Gln1870
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: DOCK5 dedicator of cytokinesis 5 [ Homo sapiens (human) ]
• Official Symbol: DOCK5
• Synonyms: DOCK5; dedicator of cytokinesis 5; dedicator of cytokinesis protein 5; FLJ21034; DKFZp451J181; DKFZp779M164; DKFZp781J211
• Gene ID: 80005
• mRNA Refseq: NM_024940
• Protein Refseq: NP_079216
• MIM: 616904
• UniProt ID: Q9H7D0