| Cat.No. : |
DOCK8-2255H |
| Product Overview : |
Recombinant Human DOCK8 Protein (560-729 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial. |
| Description : |
Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Is involved in NK cell cytotoxicity by controlling polarization of microtubule-organizing center (MTOC), and possibly regulating CCDC88B-mediated lytic granule transport to MTOC during cell killing. |
| Source : |
Yeast |
| Species : |
Human |
| Tag : |
His |
| Form : |
Tris-based buffer,50% glycerol |
| Molecular Mass : |
21.3 kDa |
| Protein length : |
560-729 aa |
| AA Sequence : |
RNLLYVYPQR LNFVNKLASA RNITIKIQFM CGEDASNAMP VIFGKSSGPE FLQEVYTAVT YHNKSPDFYE EVKIKLPAKL TVNHHLLFTF YHISCQQKQG ASVETLLGYS WLPILLNERL QTGSYCLPVA LEKLPPNYSM HSAEKVPLQN PPIKWAEGHK GVFNIEVQAV |
| Purity : |
> 85% as determined by SDS-PAGE. |
| Notes : |
Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : |
A hardcopy of COA will be sent along with the products. Please refer to it for detailed information. |
| Figure : |
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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