Recombinant Human DOK7 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | DOK7-3767H |
| Product Overview : | DOK7 MS Standard C13 and N15-labeled recombinant protein (NP_775931) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 53.2 kDa |
| AA Sequence : | MTEAALVEGQ VKLRDGKKWK SRWLVLRKPS PVADCLLMLV YKDKSERIKG LRERSSLTLE DICGLEPGLP YEGLVHTLAI VCLSQAIMLG FDSHEAMCAW DARIRYALGE VHRFHVTVAP GTKLESGPAT LHLCNDVLVL ARDIPPAVTG QWKLSDLRRY GAVPSGFIFE GGTRCGYWAG VFFLSSAEGE QISFLFDCIV RGISPTKGPF GLRPVLPDPS PPGPSTVEER VAQEALETLQ LEKRLSLLSH AGRPGSGGDD RSLSSSSSEA SHLDVSASSR LTAWPEQSSS SASTSQEGPR PAAAQAAGEA MVGASRPPPK PLRPRQLQEV GRQSSSDSGI ATGSHSSYSS SLSSYAGSSL DVWRATDELG SLLSLPAAGA PEPSLCTCLP GTVEYQVPTS LRAHYDTPRS LCLAPRDHSP PSQGSPGNSA ARDSGGQTSA GCPSGWLGTR RRGLVMEAPQ DSEATLPGPA PGEPWEAGGP HAGPPPAFFS ACPVCGGLKV NPPPTRTRPL EQKLISEEDL AANDILDYKD DDDKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | DOK7 docking protein 7 [ Homo sapiens (human) ] |
| Official Symbol : | DOK7 |
| Synonyms : | DOK7; docking protein 7; C4orf25, chromosome 4 open reading frame 25; protein Dok-7; Dok 7; FLJ33718; FLJ39137; downstream of tyrosine kinase 7; CMS1B; C4orf25; FLJ90556; |
| Gene ID : | 285489 |
| mRNA Refseq : | NM_173660 |
| Protein Refseq : | NP_775931 |
| MIM : | 610285 |
| UniProt ID : | Q18PE1 |
◆ Recombinant Protein
| Dok7-205R | Recombinant Rat Dok7 Protein, His-tagged | +Inquiry |
| Dok7-2632M | Recombinant Mouse Dok7 Protein, Myc/DDK-tagged | +Inquiry |
| DOK7-2816H | Recombinant Human DOK7 Protein, GST-tagged | +Inquiry |
| DOK7-4766M | Recombinant Mouse DOK7 Protein | +Inquiry |
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◆ Lysates
| DOK7-6843HCL | Recombinant Human DOK7 293 Cell Lysate | +Inquiry |
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