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Recombinant Human DPH5 Protein, MYC/DDK-tagged

Cat.No. : DPH5-2477H
Product Overview : Recombinant Human DPH5 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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Description : This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 31.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : DPH5 DPH5 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : DPH5
Synonyms : AD-018; CGI-30; HSPC143; NPD015
Gene ID : 51611
mRNA Refseq : NM_001077394
Protein Refseq : NP_001070862
MIM : 611075
UniProt ID : Q9H2P9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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