Recombinant Human DPH5 Protein, MYC/DDK-tagged

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Recombinant Human DPH5 Protein, MYC/DDK-tagged

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Cat.No. : DPH5-2477H
Product Overview : Recombinant Human DPH5 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 31.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : DPH5 DPH5 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : DPH5
Synonyms : AD-018; CGI-30; HSPC143; NPD015
Gene ID : 51611
mRNA Refseq : NM_001077394
Protein Refseq : NP_001070862
MIM : 611075
UniProt ID : Q9H2P9

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