Active Recombinant Human DPP4 Protein, His tagged

• Cat.No.: DPP4-27111TH
• Product Overview: Active Recombinant Human DPP4 Protein (39-766 aa) with His tag was expressed in insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 39-766 aa
• Description: The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19.
• Form: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 1mM EDTA, 10% glycerol
• Bio-activity: Specific activity is > 200 unit/mg, One unit produces 1.0 μmole of p-Nitroaniline from Gly-Pro- p-Nitroaniline per minute at pH 8.0 at 37 centigrade.
• Molecular Mass: 85.4 kDa (737aa) confirmed by MALDI-TOF
• Endotoxin: < 1 EU/μg of protein (determined by LAL method)
• Purity: > 95% by SDS-PAGE
• Applications: SDS-PAGE, Enzyme Activity
• Notes: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/mL (determined by absorbance at 280nm)

Gene Information

• Gene Name: DPP4 dipeptidyl-peptidase 4 [ Homo sapiens (human) ]
• Official Symbol: DPP4
• Synonyms: DPP4; dipeptidyl-peptidase 4; ADCP2, adenosine deaminase complexing protein 2 , CD26, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); dipeptidyl peptidase 4; DPPIV; ADCP-2; DPP IV; dipeptidylpeptidase 4; dipeptidyl peptidase IV; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); CD26; ADABP; ADCP2; TP103
• Gene ID: 1803
• mRNA Refseq: NM_001935
• Protein Refseq: NP_001926
• MIM: 102720
• UniProt ID: P27487