Recombinant Human DRC7 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DRC7-2763H
• Product Overview: CCDC135 MS Standard C13 and N15-labeled recombinant protein (NP_115645) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Involved in the regulation of flagellar motility.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 103.5 kDa
• AA Sequence: MEVLREKVEEEEEAEREEAAEWAEW ARMEKMMRPVEVRKEEITLKQETLR DLEKKLSEIQITVSAELPAFTKDTI DISKLPISYKTNTPKEEHLLQVADN FSRQYSHLCPDRVPLFLHPLNECEV PKFVSTTLRPTLMPYPELYNWDSCA QFVSDFLTMVPLPDPLKPPSHLYSS TTVLKYQKGNSFDFSTLLCSMLIGS GYDAYCVNGYGSLDLCHMDLTREVC PLTVKPKETIKKEEKVLPKKYTIKP PRDLCSRFEQEQEVKKQQEIRAQEK KRLREEEERLMEAEKAKPDALHGLR VHSWVLVLSGKREVPENFFIDPFTG HSYSTQDEHFLGIESLWNHKNYWIN MQDCWNCCKDLIFDLGDPVRWEYML LGTDKSQLSLTEEDDSGINDEDDVE NLGKEDEDKSFDMPHSWVEQIEISP EAFETRCLNGKKVIQYKRAKLEKWA PYLNSNGLVSRLTTYEDLQCTNILE IKEWYQNREDMLELKHINKTTDLKT DYFKPGHPQALRVHSYKSMQHEMDR VIEFYETARVDGLMKREETPRTMTE YYQGRPDFLSYRHASFGPRVKKLTL SSAESNPRPIVKITERFFRNPAKPA EEDVAERVFLVAEERIQLRYHCRED HITASKREFLRRTEVDSKGNKIIMT PDMCISFEVEPMEHTKKLLYQYEAM MHLKREEKLSRHQVWESELEVLEIL KLREEEEAAHTLTISIYDTKRNEKS KEYREAMERMMHEEHLRQVETQLDY LAPFLAQLPPGEKLTCWQAVRLKDE CLSDFKQRLINKANLIQARFEKETQ ELQKKQQWYQENQVTLTPEDEDLYL SYCSQAMFRIRILEQRLNRHKELAP LKYLALEEKLYKDPRLGELQKIFAT RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DRC7 dynein regulatory complex subunit 7 [ Homo sapiens (human) ]
• Official Symbol: DRC7
• Synonyms: DRC7; dynein regulatory complex subunit 7; FAP50; CFAP50; CCDC135; C16orf50; dynein regulatory complex subunit 7; coiled-coil domain containing 135; coiled-coil domain-containing protein 135; coiled-coil domain-containing protein lobo homolog
• Gene ID: 84229
• mRNA Refseq: NM_032269
• Protein Refseq: NP_115645
• MIM: 618769
• UniProt ID: Q8IY82