Recombinant Human DTNA Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human DTNA Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : DTNA-546H
Product Overview : DTNA MS Standard C13 and N15-labeled recombinant protein (NP_116761) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 58.7 kDa
AA Sequence : MIEDSGKRGN TMAERRQLFA EMRAQDLDRI RLSTYRTACK LRFVQKKCNL HLVDIWNVIE ALRENALNNL DPNTELNVSR LEAVLSTIFY QLNKRMPTTH QIHVEQSISL LLNFLLAAFD PEGHGKISVF AVKMALATLC GGKIMDKLRY IFSMISDSSG VMVYGRYDQF LREVLKLPTA VFEGPSFGYT EQSARSCFSQ QKKVTLNGFL DTLMSDPPPQ CLVWLPLLHR LANVENVFHP VECSYCHSES MMGFRYRCQQ CHNYQLCQDC FWRGHAGGSH SNQHQMKEYT SWKSPAKKLT NALSKSLSCA SSREPLHPMF PDQPEKPLNL AHIVDTWPPR PVTSMNDTLF SHSVPSSGSP FITRSMLESS NRLDEEHRLI ARYAARLAAE SSSSQPPQQR SAPDISFTID ANKQQRQLIA ELENKNREIL QEIQRLRLEH EQASQPTPEK AQQNPTLLAE LRLLRQRKDE LEQRMSALQE SRRELMVQLE GLMKLLKEEE LKQGVSYVPY CRSTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : DTNA dystrobrevin alpha [ Homo sapiens (human) ]
Official Symbol : DTNA
Synonyms : DTNA; dystrobrevin, alpha; dystrobrevin alpha; D18S892E; DRP3; DTN; DTN 1; DTN 2; DTN 3; dystrophin related protein 3; dystrophin-related protein 3; DTN-A; LVNC1; FLJ96209;
Gene ID : 1837
mRNA Refseq : NM_032979
Protein Refseq : NP_116761
MIM : 601239
UniProt ID : Q9Y4J8

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