Recombinant Human DTNB, GST-tagged

• Cat.No.: DTNB-12188H
• Product Overview: Recombinant Human DTNB protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: N-term-306a.a.
• Description: This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DTNB dystrobrevin, beta [ Homo sapiens ]
• Official Symbol: DTNB
• Synonyms: DTNB; dystrobrevin, beta; dystrobrevin beta; DTN-B; beta-dystrobrevin; MGC17163; MGC57126
• Gene ID: 1838
• mRNA Refseq: NM_001256303
• Protein Refseq: NP_001243232
• MIM: 602415
• UniProt ID: O60941
• Chromosome Location: 2p23.2
• Function: calcium ion binding; zinc ion binding