Recombinant Human DYM Protein, GST-tagged

• Cat.No.: DYM-2963H
• Product Overview: Human DYM full-length ORF (BAG52319.1, 1 a.a. - 669 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. [provided by RefSeq, Jun 2017]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 102.3 kDa
• AA Sequence: MGSNSSRIGDLPKNEYLKKLSGTES ISENDPFWNQLLSFSFPAPTSSSEL KLLEEATISVCRSLVENNPRTGNLG ALIKVFLSRTKELKLSAECQNHIFI WQTHNALFIICCLLKVFICQMSEEE LQLHFTYEEKSPGNYSSDSEDLLEE LLCCLMQLITDIPLLDITYEISVEA ISTMVVFLSCQLFHKEVLRQSISHK YLMRGPCLPYTSKLVKTLLYNFIRQ EKPPPPGAHVFPQQSDGGGLLYGLA SGVATGLWTVFTLGGVGSKAAASPE LSSPLANQSLLLLLVLANLTDASDA PNPYRQAIMSFKNTQDSSPFPSSIP HAFQINFNSLYTALCEQQTSDQATL LLYTLLHQNSNIRTYMLARTDMENL VLPILEILYHVEERNSHHVYMALII LLILTEDDGFNRSIHEVILKNITWY SERVLTEISLGSLLILVVIRTIQYN MTRTRDKYLHTNCLAALANMSAQFR SLHQYAAQRIISLFSLLSKKHNKVL EQATQSLRGSLSSNDVPLPDYAQDL NVIEEVIRMMLEIINSCLTNSLHHN PNLVYALLYKRDLFEQFRTHPSFQD IMQNIDLVISFFSSRLLQAGAELSV ERVLEIIKQGVVALPKDRLKKFPEL KFKYVEEEQPEEFFIPYVWSLVYNS AVGLYWNPQDIQLFTMDSD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DYM dymeclin [ Homo sapiens ]
• Official Symbol: DYM
• Synonyms: DYM; dymeclin; DMC; FLJ20071; SMC; dyggve-Melchior-Clausen syndrome protein; FLJ90130
• Gene ID: 54808
• mRNA Refseq: NM_017653
• Protein Refseq: NP_060123
• MIM: 607461
• UniProt ID: Q7RTS9