| Description : |
This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
76 kDa |
| AA Sequence : |
MGSNSSRIGDLPKNEYLKKLSGTES ISENDPFWNQLLSFSFPAPTSSSEL KLLEEATISVCRSLVENNPRTGNLG ALIKVFLSRTKELKLSAECQNHIFI WQTHNALFIICCLLKVFICQMSEEE LQLHFTYEEKSPGNYSSDSEDLLEE LLCCLMQLITDIPLLDITYEISVEA ISTMVVFLSCQLFHKEVLRQSISHK YLMRGPCLPYTSKLVKTLLYNFIRQ EKPPPPGAHVFPQQSDGGGLLYGLA SGVATGLWTVFTLGGVGSKAAASPE LSSPLANQSLLLLLVLANLTDASDA PNPYRQAIMSFKNTQDSSPFPSSIP HAFQINFNSLYTALCEQQTSDQATL LLYTLLHQNSNIRTYMLARTDMENL VLPILEILYHVEERNSHHVYMALII LLILTEDYGFNRSIHEVILKNITWY SERVLTEISLGSLLILVVIRTIQYN MTRTRDKYLHTNCLAALANMSAQFR SLHQYAAQRIISLFSLLSKKHNKVL EQATQSLRGSLSSNDVPLPDYAQDL NVIEEVIRMMLEIINSCLTNSLHHN PNLVYALLYKRDLFEQFRTHPSFQD IMQNIDLVISFFSSRLLQAGAELSV ERVLEIIKQGVVALPKDRLKKFPEL KFKYVEEEQPEEFFIPYVWSLVYNS AVGLYWNPQDIQLFTMDSDTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
