Recombinant Human DYRK2, GST-tagged

• Cat.No.: DYRK2-12238H
• Product Overview: Recombinant Human DYRK2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-300a.a.
• Description: DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5 terminal insert.
• Source: E.coli
• Species: Human
• Tag: GST
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [ Homo sapiens ]
• Official Symbol: DYRK2
• Synonyms: DYRK2; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2; dual specificity tyrosine-phosphorylation-regulated kinase 2; FLJ21217; FLJ21365
• Gene ID: 8445
• mRNA Refseq: NM_003583
• Protein Refseq: NP_003574
• MIM: 603496
• UniProt ID: Q92630
• Chromosome Location: 12q15
• Pathway: p53 pathway, organism-specific biosystem
• Function: ATP binding; magnesium ion binding; manganese ion binding; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity; ubiquitin binding