Recombinant Human Early Growth Response 3

• Cat.No.: EGR3-2083H
• Product Overview: Recombinant Human Early Growth Response 3 is produced inSf9 Cells.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: Non
• Description: The recombinant EGR-3 protein can be employed in the following fields of research: a) Promoter studies: Identification of EGR-3 binding promoter elements. b) Detection of EGR-3 interacting proteins. c) Signal transduction: Assay for the effect on the nuclear component EGR-3. d) Screening for EGR-3 activity in tumor cells and lines. e) Drug screening: Effect on EGR-3 generation and DNA binding.
• Purity: ≥95% (SDS-PAGE).
• Formulation: Liquid. In 20mM HEPES, pH 7.9, containing 25% glycerol, 420mM sodium chloride, 0.2mM EDTA and 1.5mM magnesium chloride.
• Specificity: Binds specifically to an oligonucleotide with the sequence GCG GGG GCG.
• Application: EMSA promoter characterization, in vitro transcription assay, analysis of nuclear extracts (oligonucleotides and recombinant protein serve as positive control).
• Storage: -80°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: EGR3 early growth response 3 [ Homo sapiens ]
• Synonyms: EGR3; early growth response 3; PILOT; MGC138484; early growth response protein 3; EGR-3; zinc finger protein pilot
• Gene ID: 1960
• mRNA Refseq: NM_004430
• Protein Refseq: NP_004421
• MIM: 602419
• UniProt ID: Q06889
• Chromosome Location: 8p23-p21
• Pathway: Cytokine-cytokine receptor interaction
• Function: metal ion binding; transcription factor activity; zinc ion binding