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Recombinant Human EARS2 Protein, His-tagged

Cat.No. : EARS2-161H
Product Overview : Recombinant Human EARS2, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.
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Description : This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : His
Form : 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Molecular Mass : 58.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : EARS2 glutamyl-tRNA synthetase 2, mitochondrial (putative) [ Homo sapiens ]
Official Symbol : EARS2
Synonyms : EARS2; glutamyl-tRNA synthetase 2, mitochondrial (putative); probable glutamate--tRNA ligase, mitochondrial; glutamate tRNA ligase 2; mitochondrial (putative); KIAA1970; MSE1; gluRS; glutamate--tRNA ligase; glutamate tRNA ligase 2, mitochondrial; probable glutamyl-tRNA synthetase, mitochondrial;
Gene ID : 124454
mRNA Refseq : NM_001083614
Protein Refseq : NP_001077083
MIM : 612799
UniProt ID : Q5JPH6

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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