Recombinant Human EDEM2 Protein, GST-tagged

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Recombinant Human EDEM2 Protein, GST-tagged

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Cat.No. : EDEM2-3051H
Product Overview : Human EDEM2 full-length ORF ( AAH01371.1, 1 a.a. - 578 a.a.) recombinant protein with GST-tag at N-terminal.
Description : In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 91.2 kDa
AA Sequence : MPFRLLIPLG LLCALLPQHH GAPGPDGSAP DPAHYRERVK AMFYHAYDSY LENAFPFDEL RPLTCDGHDT WGSFSLTLID ALDTLLILGN VSEFQRVVEV LQDSVDFDID VNASVFETNI RVVGGLLSAH LLSKKAGVEV EAGWPCSGPL LRMAEEAARK LLPAFQTPTG MPYGTVNLLH GVNPGETPVT CTAGIGTFIV EFATLSSLTG DPVFEDVARV ALMRLWESRS DIGLVGNHID VLTGKWVAQD AGIGAGVDSY FEYLVKGAIL LQDKKLMAMF LEYNKAIRNY TRFDDWYLWV QMYKGTVSMP VFQSLEAYWP GLQSLIGDID NAMRTFLNYY TVWKQFGGLP EFYNIPQGYT VEKREGYPLR PELIESAMYL YRATGDPTLL ELGRDAVESI EKISKVECGF ATIKDLRDHK LDNRMESFFL AETVKYLYLL FDPTNFIHNN GSTFDTVITP YGECILGAGG YIFNTEAHPI DPAALHCCQR LKEEQWEVED LMREFYSLKR SRSKFQKNTV SSGPWEPPAR PGTLFSPENH DQARERKPAK QKVPLLSCPS QPFTSKLALL GQVFLDSS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : EDEM2 ER degradation enhancer, mannosidase alpha-like 2 [ Homo sapiens ]
Official Symbol : EDEM2
Synonyms : EDEM2; ER degradation enhancer, mannosidase alpha-like 2; C20orf31, C20orf49, chromosome 20 open reading frame 31; ER degradation-enhancing alpha-mannosidase-like 2; bA4204.1; FLJ10783; ER degradation-enhancing-mannosidase-like protein 2; C20orf31; C20orf49;
Gene ID : 55741
mRNA Refseq : NM_001145025
Protein Refseq : NP_001138497
MIM : 610302
UniProt ID : Q9BV94

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