Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human EDN3 Protein, GST-tagged

Cat.No. : EDN3-3056H
Product Overview : Human EDN3 full-length ORF ( AAH08876, 1 a.a. - 238 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 51.92 kDa
AA Sequence : MEPGLWLLFGLTVTSAAGFVPCSQS GDAGRRGVSQAPTAARSEGDCEETV AGPGEETVAGPGEGTVAPTALQGPS PGSPGQEQAAEGAPEHHRSRRCTCF TYKDKECVYYCHLDIIWINTPEQTV PYGLSNYRGSFRGKRSAGPLPGNLQ LSHRPHLRCACVGRYDKACLHFCTQ TLDVSSNSRTAEKTDKEEEGKVEVK DQQSKQALDLHHPKLMPGSGLALAP STCPRCLFQEGAP
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : EDN3 endothelin 3 [ Homo sapiens ]
Official Symbol : EDN3
Synonyms : EDN3; endothelin 3; endothelin-3; ET3; preproendothelin-3; ET-3; WS4B; HSCR4; PPET3; MGC15067; MGC61498;
Gene ID : 1908
mRNA Refseq : NM_000114
Protein Refseq : NP_000105
MIM : 131242
UniProt ID : P14138

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All EDN3 Products

Required fields are marked with *

My Review for All EDN3 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends