| Description : |
This gene may play a role in erythroid cell differentiation. The encoded protein inhibits DNA binding of the erythroid transcription factor GATA-1 and may regulate the expression of alpha-globin and gamma-globin. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
134.7 kDa |
| AA Sequence : |
MGDAKEAGAEGPPAGAAARGGLSLL SQGESEESSAQGSALFLGGNEVKSR AVVKYSSAPPRTAFARLEEKTDLKL PPANWLRESAKLGPAGTTILGNSKK SKPFSSFGMAYDFIDSVGNDVDVVS DSENIKKLLKIPYSKSHVSMAVHRI GRTLLLDELDIQELFMRSSQTGDWT WLKEFYQRLIDQKWQRKKKSKEHWY QKAILSKFLYYSINGDGAAQPVSST AEQQESSSSDQTNDSEGASWPAPFE MPSSVSEDPSASSQGLKNDFVRNIL WTFEDIHMLVGSNMPIFGGGRYPAV SLRLRDNNKPINVLTGIDYWLDNLI CNVPELVMCFHVNGIVQKYEMIKTE EIPNLENSNFSTKVIKDIAQNILSF LKSNCTKEGHTYWLFKASGSDIVKL YDLTTLCEETEDKYQNPFTMPVAIL LYKVACNMMMKKNQNKKHYGTIRTL LLNCLKLLDKSRHPQIIASANYMLS ELFQLDEPKKEENSESPLNENSDES YSEEEEEMPDSDENGSYSTSSDPSD DSKAVAIIKSVGELSVPEKYKSIHQ IRPSCAFPVCHDTEERCRLVLSYVL EGLKSVDSSIKKESDLPAADPSTPI PLKYEDESSRGGPEGLEKQMALFLD KMGSLQKGNYSSQSGMIPGSWQHKM KLQLILKSSKAYYVLSDAAMSLQKY GRALRYIKLALQSHDTYCCLCTNML SEVLLFLSQYLTLCGDIQLMLAQNA NNRAAHLEEFHYQTKEDQEILHSLH RESSCQGFAWATDLSTDLESQLSVS CKCYEAANEILQFSDLKSQNPEHYV QVLKRMGNIRNEIGVFYMNQAAALQ SERLVSKSVSAAEQQLWKKSFSCFE KGIHNFESIEDATNAALLLCNTGRL MRICAQAHCGAGDELKREFSPEEGL YYNKAIDYYLKALRSLGTRDIHPAV WDSVNWELSTTYFTMATLQQDYAPL SRKAQEQIEKEVSEAMMKSLKYCDV DSVSARQPLCQYRAATIHHRLASMY HSCLRNQVGDEHLRKQHRVLADLHY SKAAKLFQLLKDAPCELLRVQLERV AFAEFQMTSQNSNVGKLKTLSGALD IMVRTEHAFQLIQKELIEEFGQPKS GDAAAAADASPSLNREEVMKLLSIF ESRLSFLLLQSIKLLSSTKKKTSNN IEDDTILKTNKHIYSQLLRATANKT ATLLERINVIVHLLGQLAAGSAASS NAVQTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
