| Description : |
This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
155.8 kDa |
| AA Sequence : |
MNCCRTLRELEIQVGEKVFKNIKTV MKAFELIDVNKTGLVRPQELRRVLE TFCMKLRDEEYEKFSKHYNIHKDTA VDYNVFLKNLSINNDLNLRYCMGNQ EVSLENQQAKNSKKERLLGSASSED IWRNYSLDEIERNFCLQLSKSYEKV EKALSAGDPCKGGYVSFNYLKIVLD TFVYQIPRRIFIQLMKRFGLKATTK INWKQFLTSFHEPQGLQVSSKGPLT KRNSINSRNESHKENIITKLFRHTE DHSASLKKALLIINTKPDGPITREE FRYILNCMAVKLSDSEFKELMQMLD PGDTGVVNTSMFIDLIEENCRMRKT SPCTDAKTPFLLAWDSVEEIVHDTI TRNLQAFYNMLRSYDLGDTGRIGRN NFKKIMHVFCPFLTNAHFIKLCSKI QDIGSGRILYKKLLACIGIDGPPTV SPVLVPKDQLLSEHLQKDEQQQPDL SERTKLTEDKTTLTKKMTTEEVIEK FKKCIQQQDPAFKKRFLDFSKEPNG KINVHDFKKVLEDTGMPMDDDQYAL LTTKIGFEKEGMSYLDFAAGFEDPP MRGPETTPPQPPTPSKSYVNSHFIT AEECLKLFPRRLKESFRDPYSAFFK TDADRDGIINMHDLHRLLLHLLLNL KDDEFERFLGLLGLRLSVTLNFREF QNLCEKRPWRTDEAPQRLIRPKQKV ADSELACEQAHQYLVTKAKNRWSDL SKNFLETDNEGNGILRRRDIKNALY GFDIPLTPREFEKLWARYDTEGKGH ITYQEFLQKLGINYSPAVHRPCAED YFNFMGHFTKPQQLQEEMKELQQST EKAVAARDKLMDRHQDISKAFTKTD QSKTNYISICKMQEVLEECGCSLTE GELTHLLNSWGVSRHDNAINYLDFL RAVENSKSTGAQPKEKEESMPINFA TLNPQEVVRKIQEVVESSQLALSTA FSALGKEDTGFVKATEFGQVLKDFC YKLTDNQYHYFLRKLRIHLTPYINW KYFLQNFSCFLEETADEWAEKMPKG PPPTSPKATADRDILARLHKAVTSH YHAITQEFENFDTMKTNTISREEFR AICNRRVQILTDEQFGRLWNEMPVN AKGRLKYPDFLSRFSSETAATPMAT GDSAVAQRGSSVPDVSEGTRSALSL PTQELRPGSKSQSHPCTPASTTVIP GTPPLQNCDPIESRLRKRIQGCWRQ LLKECKEKDVARQGDINASDFLALV EKFNLDISKEECQQLIIKYDLKSNG KFAYCDFIQSCVLLLKAKESSLMHR MKIQNAHKMKEAGAETPSFYSALLR IQPKIVHCWRPMRRTFKSYDEAGTG LLSVADFRTVLRQYSINLSEEEFFH ILEYYDKTLSSKISYNDFLRAFLQT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
