Recombinant Human EFR3A Protein, GST-tagged

• Cat.No.: EFR3A-3107H
• Product Overview: Human EFR3A full-length ORF ( NP_055952.1, 1 a.a. - 785 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is part of a complex that plays a role in maintaining an active pool of phosphatidylinositol 4-kinase (PI4K) at the plasma membrane. This protein is thought to be a peripheral membrane protein that associates with the plasma membrane through palmitoylation. Studies indicate that this gene product plays a role in controlling G protein-coupled receptor (GPCR) activity by affecting receptor phosphorylation. Whole exome sequencing studies have implicated mutations in this gene with autism spectrum disorders. [provided by RefSeq, Apr 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 115.2 kDa
• AA Sequence: MEKLTFYAVSAPEKLDRIGSYLAER LSRDVVRHRSGYVLIAMEALDQLLM ACHSQSIKPFVESFLHMVAKLLESG EPKLQVLGTNSFVKFANIEEDTPSY HRRYDFFVSRFSAMCHSCHSDPEIR TEIRIAGIRGIQGVVRKTVNDELRA TIWEPQHMDKIVPSLLFNMQKIEEV DSRIGPPSSPSATDKEENPAVLAEN CFRELLGRATFGNMNNAVRPVFAHL DHHKLWDPNEFAVHCFKIIMYSIQA QYSHHVIQEILGHLDARKKDAPRVR AGIIQVLLEAVAIAAKGSIGPTVLE VFNTLLKHLRLSVEFEANDLQGGSV GSVDLNTSSKDNDEKIVQNAIIQTI GFFGSNLPDYQRSEIMMFIMGKVPV FGTSTHTLDISQLGDLGTRRIQIML LRSLLMVTSGYKAKTIVTALPGSFL DPLLSPSLMEDYELRQLVLEVMHNL MDRHDNRAKLRGIRIIPDVADLKIK REKICRQDTSFMKKNGQQLYRHIYL GCKEEDNVQKNYELLYTSLALITIE LANEEVVIDLIRLAIALQDSAIINE DNLPMFHRCGIMALVAAYLNFVSQM IAVPAFCQHVSKVIEIRTMEAPYFL PEHIFRDKCMLPKSLEKHEKDLYFL TNKIAESLGGSGYSVERLSVPYVPQ VTDEDRLSRRKSIVDTVSIQVDILS NNVPSDDVVSNTEEITFEALKKAID TSGMEEQEKEKRRLVIEKFQKAPFE EIAAQCESKANLLHDRLAQILELTI RPPPSPSGTLTITSGHAQYQSVPVY EMKFPDLCVY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EFR3A EFR3 homolog A (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: EFR3A
• Synonyms: EFR3A; EFR3 homolog A (S. cerevisiae); protein EFR3 homolog A; KIAA0143; DKFZp781J0562
• Gene ID: 23167
• mRNA Refseq: NM_015137
• Protein Refseq: NP_055952
• MIM: 611798
• UniProt ID: Q14156