Recombinant Human EGLN2 Protein, GST-tagged

• Cat.No.: EGLN2-3118H
• Product Overview: Human EGLN2 full-length ORF ( AAH36051, 1 a.a. - 407 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 70.51 kDa
• AA Sequence: MDSPCQPQPLSQALPQLPGSSSEPL EPEPGRARMGVESYLPCPLLPSYHC PGVPSEASAGSGTPRATATSTTASP LRDGFGGQDGGELRPLQSEGAAALV TKGCQRLAAQGARPEAPKRKWAEDG GDAPSPSKRPWARQENQEAEREGGM SCSCSSGSGEASAGLMEEALPSAPE RLALDYIVPCMRYYGICVKDSFLGA ALGGRVLAEVEALKRGGRLRDGQLV SQRAIPPRSIRGDQIAWVEGHEPGC RSIGALMAHVDAVIRHCAGRLGSYV INGRTKAMVACYPGNGLGYVRHVDN PHGDGRCITCIYYLNQNWDVKVHGG LLQIFPEGRPVVANIEPLFDRLLIF WSDRRNPHEVKPAYATRYAITVWYF DAKERAAAKDKYQLASGQKGVQVPV SQPPTPT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EGLN2 egl nine homolog 2 (C. elegans) [ Homo sapiens ]
• Official Symbol: EGLN2
• Synonyms: EGLN2; egl nine homolog 2 (C. elegans); EGL nine (C.elegans) homolog 2; egl nine homolog 2; HIF prolyl hydroxylase 1; HIFPH1; PHD1; estrogen-induced tag 6; HIF-prolyl hydroxylase 1; hypoxia-inducible factor prolyl hydroxylase 1; prolyl hydroxylase domain-containing protein 1; EIT6; HPH-1; HPH-3; HIF-PH1; FLJ95603; DKFZp434E026
• Gene ID: 112398
• mRNA Refseq: NM_053046
• Protein Refseq: NP_444274
• MIM: 606424
• UniProt ID: Q96KS0