Recombinant Human EGR2 Protein, GST-tagged

• Cat.No.: EGR2-3123H
• Product Overview: Human EGR2 full-length ORF ( NP_000390.2, 1 a.a. - 476 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 76.7 kDa
• AA Sequence: MMTAKAVDKIPVTLSGFVHQLSDNI YPVEDLAATSVTIFPNAELGGPFDQ MNGVAGDGMINIDMTGEKRSLDLPY PSSFAPVSAPRNQTFTYMGKFSIDP QYPGASCYPEGIINIVSAGILQGVT SPASTTASSSVTSASPNPLATGPLG VCTMSQTQPDLDHLYSPPPPPPPYS GCAGDLYQDPSAFLSAATTSTSSSL AYPPPPSYPSPKPATDPGLFPMIPD YPGFFPSQCQRDLHGTAGPDRKPFP CPLDTLRVPPPLTPLSTIRNFTLGG PSAGVTGPGASGGSEGPRLPGSSSA AAAAAAAAAYNPHHLPLRPILRPRK YPNRPSKTPVHERPYPCPAEGCDRR FSRSDELTRHIRIHTGHKPFQCRIC MRNFSRSDHLTTHIRTHTGEKPFAC DYCGRKFARSDERKRHTKIHLRQKE RKSSAPSASVPAPSTASCSGGVQPG GTLCSSNSSSLGGGPLAPCSSRTRT P
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EGR2 early growth response 2 [ Homo sapiens ]
• Official Symbol: EGR2
• Synonyms: EGR2; early growth response 2; early growth response 2 (Krox 20 homolog, Drosophila) , KROX20; E3 SUMO-protein ligase EGR2; Krox 20 homolog; Drosophila; zinc finger protein Krox-20; early growth response protein 2; KROX-20, Drosophila, homolog (early growth response-2); AT591; CMT1D; CMT4E; KROX20; FLJ14547; DKFZp686J1957
• Gene ID: 1959
• mRNA Refseq: NM_000399
• Protein Refseq: NP_000390
• MIM: 129010
• UniProt ID: P11161