Recombinant Human EHMT1 Protein, GST-tagged


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Recombinant Human EHMT1 Protein, GST-tagged

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Cat.No. : EHMT1-006H
Product Overview : Recombinant Human EHMT1 protein with a N-terminal GST-tag was expressed in E. coli
Description : The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : 60.3 kDa
Purity : ≥95% estimated by SDS-PAGE
Unit Definition : One unit is defined as the amount of enzyme required to transfer one methyl group to Histone H3 per minute as determined using 100 µM Histone H3 (1-21) peptide at 37 centigrade using Methyltransferase Colorimetric Assay Kit.
Stability : ≥ 545 days
Storage : -80 centigrade
Shipping : Dry ice in continental US, may vary elsewhere.
EHMT1 enzyme titration :

SDS-PAGE analysis of EHMT1. :

Lane 1: MW Markers
Lane 2: GLP (1 µg)
Lane 3: GLP (2 µg)
Lane 4: GLP (5 µg)

Gene Name : EHMT1 euchromatic histone lysine methyltransferase 1 [ Homo sapiens (human) ]
Official Symbol : EHMT1
Synonyms : EHMT1; euchromatic histone lysine methyltransferase 1; GLP; GLP1; KMT1D; KLEFS1; FP13812; EHMT1-IT1; EUHMTASE1; Eu-HMTase1; histone-lysine N-methyltransferase EHMT1; EHMT1 intronic transcript 1; G9a-like protein 1; H3-K9-HMTase 5; euchromatic histone-lysine N-methyltransferase 1; histone H3-K9 methyltransferase 5; histone-lysine N-methyltransferase, H3 lysine-9 specific 5; lysine N-methyltransferase 1D; EC
Gene ID : 79813
mRNA Refseq : NM_024757
Protein Refseq : NP_079033
MIM : 607001
UniProt ID : Q9H9B1
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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