Recombinant Human EHMT1 Protein, GST-tagged EHMT1-006H

Recombinant Human EHMT1 Protein, GST-tagged

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Recombinant Human EHMT1 Protein, GST-tagged

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Cat.No. : EHMT1-006H
Product Overview : Recombinant Human EHMT1 protein with a N-terminal GST-tag was expressed in E. coli
Description : The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : 60.3 kDa
Purity : ≥95% estimated by SDS-PAGE
Unit Definition : One unit is defined as the amount of enzyme required to transfer one methyl group to Histone H3 per minute as determined using 100 µM Histone H3 (1-21) peptide at 37 centigrade using Methyltransferase Colorimetric Assay Kit.
Stability : ≥ 545 days
Storage : -80 centigrade
Shipping : Dry ice in continental US, may vary elsewhere.
EHMT1 enzyme titration :

SDS-PAGE analysis of EHMT1. :

Lane 1: MW Markers
Lane 2: GLP (1 µg)
Lane 3: GLP (2 µg)
Lane 4: GLP (5 µg)

Gene Name : EHMT1 euchromatic histone lysine methyltransferase 1 [ Homo sapiens (human) ]
Official Symbol : EHMT1
Synonyms : EHMT1; euchromatic histone lysine methyltransferase 1; GLP; GLP1; KMT1D; KLEFS1; FP13812; EHMT1-IT1; EUHMTASE1; Eu-HMTase1; histone-lysine N-methyltransferase EHMT1; EHMT1 intronic transcript 1; G9a-like protein 1; H3-K9-HMTase 5; euchromatic histone-lysine N-methyltransferase 1; histone H3-K9 methyltransferase 5; histone-lysine N-methyltransferase, H3 lysine-9 specific 5; lysine N-methyltransferase 1D; EC 2.1.1.43
Gene ID : 79813
mRNA Refseq : NM_024757
Protein Refseq : NP_079033
MIM : 607001
UniProt ID : Q9H9B1

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