Recombinant Human EHMT2, GST-tagged

• Cat.No.: EHMT2-427H
• Product Overview: Recombinant Human G9a (euchromatic histone-lysine N-methyltransferase 2) (amino-acids 785-1210), with N-terminal GST tag expressed inE.Coliexpression system. MW = 74.6 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 785-1210 a.a.
• Description: Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 is an enzyme that in humans is encoded by the EHMT2 gene. A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster; it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair.
• Purity: >70%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
• Stability: >6 months at –80°C.

Gene Information

• Gene Name: EHMT2 euchromatic histone-lysine N-methyltransferase 2 [ Homo sapiens ]
• Synonyms: EHMT2; euchromatic histone-lysine N-methyltransferase 2; G9A; BAT8; NG36; KMT1C; C6orf30; FLJ35547; DKFZp686H08213; G9A histone methyltransferase; H3-K9-HMTase 3; HLA-B associated transcript 8; ankyrin repeat-containing protein; histone H3-K9 methyltransferase 3; lysine N-methyltransferase 1C; protein G9a; EC 2.1.1.43
• Gene ID: 10919
• mRNA Refseq: NM_006709
• Protein Refseq: NP_006700
• MIM: 604599
• UniProt ID: Q96KQ7
• Chromosome Location: 6p21.31
• Pathway: Lysine degradation
• Function: histone-lysine N-methyltransferase activity; metal ion binding; methyltransferase activity; protein binding; transferase activity; zinc ion binding