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Recombinant Human EIF4EBP3 Protein (1-100 aa), His-SUMO-tagged

Cat.No. : EIF4EBP3-476H
Product Overview : Recombinant Human EIF4EBP3 Protein (1-100 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Full Length.
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  • Gene Information
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Description : Repressor of translation initiation that regulates EIF4E activity by preventing its assbly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.
Source : E. coli
Species : Human
Tag : His-SUMO
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 26.9 kDa
Protein length : 1-100 aa
AA Sequence : MSTSTSCPIPGGRDQLPDCYSTTPG GTLYATTPGGTRIIYDRKFLLECKN SPIARTPPCCLPQIPGVTTPPTAPL SKLEELKEQETEEEIPDDAQFEMDI
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Gene Name : EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 [ Homo sapiens ]
Official Symbol : EIF4EBP3
Synonyms : EIF4EBP3; 4E BP3; 4EBP3; 4E-BP3;
Gene ID : 8637
mRNA Refseq : NM_003732
Protein Refseq : NP_003723
MIM : 603483
UniProt ID : O60516

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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