Recombinant Human EIF4G3 Protein, GST-tagged

• Cat.No.: EIF4G3-3212H
• Product Overview: Human EIF4G3 full-length ORF ( AAH30578, 1 a.a. - 515 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 82.39 kDa
• AA Sequence: MNSQPQTRSPFAAGPRPPHHQFFQR PQIQPPRATIPNSSPSIRPGAQTPT AVYQANQHIMMVNHLPMPYPVPQGP QYCIPQYRHSGPPYVGPPQQYPVQP PGPGPFYPGPGPGDFPNAYGTPFYP SQPVYQSAPIMVPTQQQPPPAKREK KTIRIRDPNQGGKDITEEIISGGGS RNPTPPIGRPTSTPTPPQQLPSQVP EHSPVVYGTVESAHLAASTPVTAAS DQKQEEKPKPDPVLKSPSPVLRLVL SGEKKEQEGQTSETTAIVSIAELPL PPSPTTVSSVARSTIAAPTSSALSS QPIFTTAIDDRCELSSPREDTIPIP SLTSCTETSDPLPTNENDGDICKKP CSVAPNDIPLVSSTNLINEINGVSE KLSATESIVEIVKQEVLPLTLELEI LENPPEEMKLECIPAPITPSTVPSF PPTPPTPPASPPHTPVIVPAAATTV SSPSAAITVQRVLEEDESIRTCLSE DAKEIQNKIEVEADGQTEEILDSQN LNSRRSPVPETSNEC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 [ Homo sapiens ]
• Official Symbol: EIF4G3
• Synonyms: EIF4G3; eukaryotic translation initiation factor 4 gamma, 3; eukaryotic translation initiation factor 4 gamma 3; eIF4GII; eIF-4-gamma 3; eIF-4-gamma II; eIF4G 3; eIF-4G 3
• Gene ID: 8672
• mRNA Refseq: NM_001198801
• Protein Refseq: NP_001185730
• MIM: 603929
• UniProt ID: O43432