| Description : |
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
83.8 kDa |
| AA Sequence : |
MPPPADIVKVAIEWPGAYPKLMEID QKKPLSAIIKEVCDGWSLANHEYFA LQHADSSNFYITEKNRNEIKNGTIL RLTTSPAQNAQQLHERIQSSSMDAK LEALKDLASLSRDVTFAQEFINLDG ISLLTQMVESGTERYQKLQKIMKPC FGDMLSFTLTAFVELMDHGIVSWDT FSVAFIKKIASFVNKSAIDISILQR SLAILESMVLNSHDLYQKVAQEITI GQLIPHLQGSDQEIQTYTIAVINAL FLKAPDERRQEMANILAQKQLRSII LTHVIRAQRAINNEMAHQLYVLQVL TFNLLEDRMMTKMDPQDQAQRDIIF ELRRIAFDAESEPNNSSGSMEKRKS MYTRDYKKLGFINHVNPAMDFTQTP PGMLALDNMLYFAKHHQDAYIRIVL ENSSREDKHECPFGRSSIELTKMLC EILKVGELPSETCNDFHPMFFTHDR SFEEFFCICIQLLNKTWKEMRATSE DFNKVMQVVKEQVMRALTTKPSSLD QFKSKLQNLSYTEILKIRQSERMNQ EDFQSRPILELKEKIQPEILELIKQ QRLNRLVEGTCFRKLNARRRQDKFW YCRLSPNHKVLHYGDLEESPQGEVP HDSLQDKLPVADIKAVVTGKDCPHM KEKGALKQNKEVLELAFSILYDSNC QLNFIAPDKHEYCIWTDGLNALLGK DMMSDLTRNDLDTLLSMEIKLRLLD LENIQIPDAPPPIPKEPSNYDFVYD CNTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
