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Recombinant Human ELN Protein, GST-tagged

Cat.No. : ELN-3259H
Product Overview : Human ELN full-length ORF (1 a.a. - 335 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a protein that is one of the two components of elastic fibers. Elastic fibers comprise part of the extracellular matrix and confer elasticity to organs and tissues including the heart, skin, lungs, ligaments, and blood vessels. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Degradation products of the encoded protein, known as elastin-derived peptides or elastokines, bind the elastin receptor complex and other receptors and stimulate migration and proliferation of monocytes and skin fibroblasts. Elastokines can also contribute to cancer progression. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. [provided by RefSeq, Aug 2017]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 55.4 kDa
AA Sequence : MAGLTAAAPRPGVLLLLLSILHPSR PGGVPGAIPGGVPGGVFYPGAGLGA LGGGALGPGGKPLKPVPGGLAGAGL GAGLGAFPAVTFPGALVPGGAAAKA AAKFGAGAAGVLPGVGGAGVPGVPG AIPGIGGIAGVGTPAAAAAAAAAAK AAKYGAAAGLVPGGPGFGPGVVGVP GAGVPGVGVPGAGIPVVPGAGIPGA AVPGVVSPEAAAKAAAKAAKYGARP GVGVGGIPTYGALGGVGIPGGVVGA GPAAAAAAAKAAAKAAQFGLVGAAG LGGLGVGGLGVPGVGGLGGIPPAAA AKAAKYGVAARPGFGLSPIFPGGAC LGKACGRKRK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ELN elastin [ Homo sapiens ]
Official Symbol : ELN
Synonyms : ELN; elastin; supravalvular aortic stenosis; SVAS; tropoelastin; WBS; Williams Beuren syndrome; WS; FLJ38671; FLJ43523;
Gene ID : 2006
mRNA Refseq : NM_000501
Protein Refseq : NP_000492
MIM : 130160
UniProt ID : P15502

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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